If using cauliflower from frozen, cook cauliflower according to package directions. Let cool slightly, then squeeze out as much moisture as possible using a clean kitchen towel.
In a bowl, mix cauliflower, eggs, mozzarella, parmesan, Italian seasoning, garlic powder, and salt.
Generously grease a metal muffin tin. Fill each cup about ¾ full and press firmly. Top with mozzarella cheese, jalapenos and pepperoni.
Bake at 400F for 22-25 minutes until golden and set. Let rest 5 minutes before removing. Serve warm.